Both clubs have undergone massive changes since, and find themselves in very opposite phases at the moment. Bayern are looking to win their seventh Bundesliga title in a row while Chelsea – affected by a transfer ban – are fighting to finish in the Champions League spots in the Premier League.
Chelsea head into the match on the back of a morale-boosting win over Tottenham Hotspur. Meanwhile, the German outfit make the trip to Stamford Bridge having maintained the top spot in the Bundesliga with a hard-fought triumph against Paderborn.
Here are the three things to look forward to as Chelsea host Bayern Munich in the Champions League.
3. Are Chelsea's youngsters up for the challenge?
Chelsea will once again be without the services of Christian Pulisic and Callum Hudson-Odoi, while midfielder N’Golo Kante is also set to miss out due to the adductor injury he picked up against Manchester United earlier this month. Tammy Abraham returned to action on Saturday, playing 20 minutes off the bench in the win against Spurs.
Frank Lampard's youngsters have done the double over Jose Mourinho's side this season, and that will, no doubt, fill them with the confidence they need going into this game. And while their European form hasn’t been perfect, Blues fans have been treated to some outstanding games.
Top of that list would be Chelsea’s crazy 4-4 draw with Ajax, a match that saw them come from behind after trailing 1-4 to pick up an all-important point.
2. Flick's future hangs in the balance
Hans Flick is aware that there is a demand for further progress in the Champions League after last season's last-16 exit, which made it six campaigns in a row in which Bayern had failed to reach the final. The visitors will be well aware that there is a window of opportunity, especially against opponents who have found it difficult on their home patch.
Tuesday's contest will mark the second time that Bayern have made the trip to London in under six months after thrashing Spurs by a 7-2 scoreline during the group stages. The interim manager will have to decide whether Thomas Muller gets to start or a pacey winger and whether to go with Jerome Boateng or go with Lucas Hernandez and David Alaba – which will mean two left-footed centre-backs for the Bundesliga champions.
Chelsea’s full-backs leave a lot of space when they go forward, and it wouldn't be surprising to see Muller start, and in all fairness, the man does have 15 assists to his name this season.
1. How do Chelsea stop Lewandowski and Gnabry?
It's safe to say that Robert Lewandowski and Serge Gnabry are having a ball this season. The Polish striker has already netted 38 goals and registered three assists in the 32 games he has played this season across competitions. Gnabry, too, has been consistently good this season, bagging 15 goals and 10 assists in the 29 games he has played so far in this season. And the former Arsenal youngster scored a splendid hat-trick against Tottenham in the last round.
Chelsea will have to be extra cautious when dealing with both these men, because if one is dangerous, both of them together are absolutely lethal. With Antonio Rudiger and Andreas Christensen back in the side, the Blues will be looking to man-mark both players out of the game. Bayern have been winning games in cruise control in recent weeks.
While Chelsea have the ability to offer a sterner test, Lampard’s side are infamously fragile at the back and face 90 minutes against arguably the most prolific striker in world football.