Inter Milan needed to win against Barcelona to qualify for the next round of the Champions League, but goals from Carlos Perez and Ansu Fati saw the current Serie A leaders dumped out of the competition.
Inter, who were level on points with Borussia Dortmund, needed a win or a draw (if Dortmund lost or drew) to help them qualify, and it looked as if they were on the right track, but hordes of missed chances and offsides ultimately ended Antonio Conte's Champions League journey this campaign.
There were some strong performances from Barca’s youngsters as Ernesto Valverde rested virtually all his regular starters, while Inter let the occasion get the better of them and can have no complaints about their premature exit.
Here are three things we learned as Barcelona beat Inter 2-1 at the San Siro.
3. Inter Architects of Their Own Downfall
History seems to be repeating for Inter who went out of the Champions League last year in similar fashion, where they only managed a draw with PSV at home, leading to their elimination at the expense of Tottenham.
Inter got the ball in the back of the net on three occasions but all were rightly ruled out for offside, but beyond those, they did not utilize their opportunities, with Romelu Lukaku being the chief culprit with his profligacy in front of goal. Lautaro Martinez linked up beautifully with Lukaku to score Inter's first goal, but it seemed like an off night for the 22-year-old.
2. Barca's Second-String Are a Good Backup
With Lionel Messi, Gerard Pique, and Sergi Roberto left back at home for this game, Ernesto Valverde picked an extremely young side, handing starts to youngsters Moussa Wague, Jean-Claire Todibo, and Carles Perez.
And while they did come up against Inter's first-team squad, these Barca young'uns did not fail to impress. Perez trumped Antoine Griezmann in attack and opened the scoring on his Champions League debut. Backup keeper Neto was fantastic between the sticks, pulling off some important saves, and putting in a potential Man of the Match performance for the visitors.
1. Time for Conte to Focus on the Scudetto
Antonio Conte's men might have dropped down to the Europa League but they're still on top of the Serie A table, two points ahead of defending champions, Juventus. This is the closest the Nezzuri have got to toppling the Old Lady in the last decade, and Inter have to give it their all.
The Bianconeri picked up their first loss of the season when they fell 3-1 to Lazio, and while Inter found themselves struggling against AS Roma, there's a definite feeling in the camp that maybe, just maybe, this could be their year.